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Baked Cajun Salmon | Creamy Avocado Lime Sauce

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Fire and ice! Flaky salmon, perfectly baked at 400°F, gets a kick from Cajun spice, cooled by a creamy avocado-lime drizzle. Full instructions and nutritional facts provided.

  • Total Time: 35 minutes
  • Yield: 4 servings 1x

Ingredients

Scale
  • 4 (6 oz) skin-on salmon fillets
  • 2 tablespoons Cajun seasoning blend
  • 1 tablespoon olive oil
  • 1 large ripe avocado
  • 2 tablespoons fresh lime juice
  • 1/4 cup fresh cilantro, chopped
  • 1/4 cup plain Greek yogurt or sour cream
  • 1/2 teaspoon garlic powder

Instructions

  1. Step 1: Preheat the oven to 400°F (200°C). Line a baking sheet with parchment paper or foil. Rub the salmon fillets lightly with olive oil, then generously coat all sides of the fish with the Cajun seasoning blend.
  2. Step 2: Place the seasoned salmon fillets skin-side down on the prepared baking sheet. Bake for 12–15 minutes, or until the internal temperature reaches 145°F (63°C) and the fish flakes easily with a fork.
  3. Step 3: While the salmon is baking, prepare the creamy avocado lime sauce. Combine the flesh of the ripe avocado, fresh lime juice, chopped cilantro, Greek yogurt, and garlic powder in a small food processor or high-powered blender.
  4. Step 4: Process the sauce mixture until it is completely smooth and creamy, stopping to scrape down the sides as needed. If the sauce is too thick, add 1 teaspoon of water or milk at a time until the desired drizzling consistency is achieved.
  5. Step 5: Remove the baked Cajun salmon from the oven and allow it to rest for 2 minutes. Plate the salmon and immediately drizzle the cool, creamy avocado lime sauce generously over the top before serving.

Notes

  • Store leftover avocado sauce in an airtight container with plastic wrap pressed directly onto the surface to block air and keep it green for up to two days.
  • Reheat the salmon gently by wrapping it loosely in foil with a teaspoon of water or broth, warming it in a 300°F oven until just heated through to maintain moisture.
  • Serve this spicy and creamy salmon atop a bed of fluffy cilantro-lime rice or alongside charred broccolini for a complete and flavorful meal.
  • For a deeply flavorful crust, make sure to pat the salmon fillets completely dry before rubbing them with olive oil and the Cajun seasoning blend.
  • Author: Kristin Romick
  • Prep Time: 15 minutes
  • Cook Time: 20 minutes
  • Method: Stovetop
  • Cuisine: American